Illumina and PacBio Sequencing of Human and Mouse DNA and RNA

The Mechanistic Studies Division (MSD) of Health Canada’s Environmental Health Research and Science Bureau investigates the pathways by which physical, chemical and microbiological agents can cause adverse health effects. To determine how chemical substances cause DNA damage that can lead to illnesses like cancer or inherited diseases, MSD requires high-throughput genome sequencing services utilizing Illumina and Pacific Biosciences (PacBio) platforms. The primary objective of this contract is to secure long-term high-quality sequencing services for pre-prepared DNA libraries and genomic DNA and/or RNA utilizing Illumina or PacBio Revio platforms for the full duration of projects funded until up to 2030-2031. This requirement encompasses the sequencing of multiple mouse and human error-corrected next-generation sequencing (ecNGS) DNA libraries, genomic DNA and/or RNA samples in direct support of four distinct research projects. These projects are distributed across the Division and funded through three separate programs. Collectively, they employ advanced genomic technologies to support public health protection by identifying environmental mutagens, evaluating occupational hazards, and improving toxicological testing methodologies. Specifically, this work will use ecNGS, whole-genome sequencing (WGS), whole-exome sequencing and/or RNA-sequencing approaches to detect and characterize both spontaneous mutations and mutations induced by chemical and environmental exposures in mouse and human DNA as well as gene expression changes. The resulting data will contribute to a better understanding of mutagenic mechanisms, exposure-related genetic damage, and the development of more sensitive and informative approaches for genetic toxicology and human health risk assessment.

Category: SRV

• Procurement method: Competitive - Open bidding
• Briefing session: Not captured. Check the original notice before relying on this.
• Eligibility and evaluation: set out in the tender documents. Check mandatory returnables, registrations and scoring before you commit.

The tender pack is published with the original notice. Use “Download Tender Pack” to open it.

Published

03 Nov 2026

First seen by Atlas

05 Nov 2026

Briefing session

Not captured. Check the original notice before relying on this.

Submission deadline

03 Dec 2026, 16:00 SAST

Estimated value

Not stated in the notice

Contract type

Competitive - Open bidding

Category

SRV

Source

CanadaBuys

• Manage the Bid: A structured response, from the opportunity decision to the final submission.
• Develop the Response: Clear writing, considered production and approved material ready for reuse.
• Build Bid Capability: Practical support that strengthens how your business prepares and responds.